We study the neural circuits that mediate auditory cognition. Our goal is to understand how we assign meaning to sounds, how we attend to sounds or ignore them, how we remember them, and how disorders of the brain can affect these processes.
Of particular interest is how our responses to sounds can change depending on context, a phenomenon called behavioral flexibility. Behaving appropriately after changes in context requires that organisms rapidly modify their expectations, associations between cues and rewards, or attentional state. Our lab investigates these cognitive processes by addressing three questions:
  • What happens to the speed and accuracy of behavioral responses after a change in context?
  • Where in the brain is information selected and re-routed to allow for different interpretations of the same stimulus?
  • How do neural circuits implement this flexibility?
In our experiments, we use tools for monitoring and manipulating neuronal activity of specific cell types in behaving rodents, together with theoretical and computational approaches, to uncover the mechanisms that underlie flexible behaviors.

Members


Santiago Jaramillo
Principal Investigator
Dept. of Biology
member
Lan Guo
Postdoctoral fellow
member
Nick Ponvert
Graduate student
member
Anna Lakunina
Graduate student
member
Phoebe Penix
Research assistant

member
Victoria Russell
Undergrad researcher
member
Zurui Yu
Undergrad researcher
member
Sadie Lang
Undergrad researcher
member
Kyle Wilburn
Undergrad researcher
mouse
Mus musculus
Subject of choice

Selected publications